Filip Jorgensen starts in goal. Axel Disasi, Tosin Adarbioyo, Benoit Badiashile, and Renato Veiga line up in a back four that could turn into a back three if Veiga changes his strategy.
Moisés Caicedo will begin as the deepest midfielder with Kiernan Desbury-Hall as the standard midfielder, while Christopher Nkunku will play as the CM/CAM hybrid.
Pedro Neto makes his debut as a starter on the right flank, while Mykhailo Mudryk is on the left and young Marc Guiu is up front.
Complete starting lineup: Jorgensen, Disasi, Tosin, Badiashile, Veiga, Caicedo (c), Dewsury-Hall, Nkunku, Mudryk, Neto, Guiu
Maresca debuts an almost entirely new lineup. Nkunku moves inside to take on a more central role after playing on the left against Manchester City. This formation will likely be more similar to the one used at the beginning of preseason, with Neto and Mudryk providing width while Disasi tucks in from the right flank to form a back three. Veiga will switch positions to form a defensive midfield duo with Caicedo.
